Yongjian Liu

Yongjian Liu

Yongjian Liu

Assistant Professor of Radiology
4402C Clinical Sciences Research Building
p: 314.362.8431

My research focuses on the development of novel molecular probes for preclinical and clinical diagnosis and therapy.

Education

PhD, Chemistry, University of Missouri, Columbia, Missouri 2007

MS, Environmental Science, Zhejiang University, Hangzhou, China 2000

BS, Chemistry, Henan Normal University, Xinxiang, China 1997

Research

Evaluation of nanoparticle based agents for pre-clinical imaging and therapy

Development of biomolecules for translational PET imaging

Assessment of Cherenkov imaging for biomedical applications

Publications (selected)

1)      Yongjian Liu, Dana Abendschein, Geoffrey Woodard, Raffaella Rossin, Kyle McCommis, Jie Zheng, Michael Welch, Pamela Woodard. Molecular Imaging of Atherosclerotic Plaque with 64Cu-Labeled Natriuretic Peptide and Positron Emission Tomography. Journal of Nuclear Medicine, 2010, 51, 85-91.

2)      Yongjian Liu, Eric Pressly, Dana Abendschein, Craig Hawker, Geoffrey Woodard, Pamela Woodard, Michael Welch. Targeting Angiogenesis Using a C-type Atrial Natriuretic Factor Conjugated Nanoprobe and Positron Emission Tomography. Journal of Nuclear Medicine, 2011, 52, 1956-1963.

3)      Dexing Zeng, Nam Lee, Yongjian Liu, Dong Zhou, Carmen Dence, Karen Wooley, John A Katzenellenbogen, Michael Welch. 64Cu Core-labeled Nanoparticles with High Specific Activity via Metal-free Click Chemistry. ACS Nano, 2012, 6, 5209-5219.

4)      Yucai Wang, Yongjian Liu, Hannah Luehmann, Xiaohu Xia, Paige Brown, Chad Jarreau, Michael Welch, Younan Xia. Evaluating the Pharmacokinetics and In Vivo Cancer Targeting Capability of Au Nanocages by Positron Emission Tomography Imaging. ACS Nano, 2012, 6, 5880-5888.

5)      Ang Li, Hannah Luehmann, Guorong Sun, Sandani Samarajeewa, Jiong Zou, Shiyi Zhang, Fuwu Zhang, Michael J. Welch, Yongjian Liu, Karen L. Wooley. Synthesis and In Vivo Pharmacokinetic Evaluation of Degradable Shell Crosslinked Polymer Nanoparticles with Poly(carboxybetaine) vs. Poly(ethylene glycol)  Surface grafted Coatings. ACS Nano, 2012, 6, 8970-8982.

6)      Ritu Shrestha, Mahmoud Elsabahy, Hannah Leuhmann, Sandani Samarajeewa,  Stephanie Florez-Malaver, Nam S. Lee, Michael J. Welch, Yongjian Liu, Karen L. Wooley. Hierarchically Assembled Theranostic Nanostructures for siRNA Delivery and Imaging Applications. Journal of American Chemical Society, 2012, 134, 17362-17365.

7)      Yucai Wang, Yongjian Liu, Hannah Luehmann, Yu Zhang, Cathy Cutler, Younan Xia. Radioluminescent Gold Nanocages with Controlled Radioactivity for Real-time Imaging In Vivo. Nano Letters, 2013, 13, 581-585.

8)      Eric Pressly, Rich Pierce, Luke A Connal, Craig J. Hawker, Yongjian Liu. Nanoparticle PET/CT Imaging of Natriuretic Peptide Clearance Receptor in Prostate Cancer. Bioconjugate Chemistry, 2013, 24, 196-204.

9)Yucai Wang, Kvar C.L. Black, Hannah Luehmann, Weiyang Li, Yu Zhang, Xin Cai, Dehui Wan, Si-Yun Liu, Max Li, Paul Kim, Zhi-Yuan Li, Lihong V. Wang, Yongjian Liu, Younan Xia.  Comparison Study of Gold Nanohexapods, Nanorods, and Nanocages for Photothermal Cancer Treatment. ACS Nano, 2013, 7, 2068-2077.

10)  Yongjian Liu, Richard Pierce, Hannah Luehmann, Terry L. Sharp, Michael J. Welch. Positron Emission Tomography Imaging of Chemokine Receptors in Vascular Injury Accelerated Atherosclerosis. Journal of Nuclear Medicine, 2013, 7, 1135-1141.